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The YouTuber went through eight rounds with Mayweather, who dominated the contest, but no winner was declared.
Paul showed plenty of respect to Mayweather after the fight, however that appears to be all in the past now with the 26-year-old demanding the money he is owed by the boxing icon.
The message to Mayweather was clear to see in an expletive message to the multiple world champion winning boxer.
"Pay me my money you f***ing cornball of a human," Paul said in an Instagram story, tagging the man himself and photoshopping a less than flattering pic of the boxing legend from his recent trip to Russia.
The Mirror reports that the bout between Paul and Mayweather registered more than a million pay-per-view buys for the showdown in Miami.
Paul gained plenty of respect following the fight, especially after Mayweather made light work of kickboxer Tenshin Nasukawa in his previous exhibition bout.
Mayweather dashed any hopes that he would enter the ring again in the immediate aftermath of his fight with Paul, and said: "I am going into the Hall of Fame; I have nothing to prove."
"If they are happy with grappling and holding for eight rounds, that's good for them - I hope the fans were pleased.
"I have been in this sport for so long, I was letting people see I can come out at the age of 44 and bring 30,000 to the stadium and bring good pay-per-view numbers.
"I am not going to perform like I was 19, it's all about growth and ageing - I can't fight like when I fought people like Gatti and people like that.
"His whole goal was to survive and that was a win for him; if he's happy, so be it. In the history books I will always be the greatest.
"Will I make a comeback? Absolutely not. I have retired from the sport of boxing. I probably won't do an exhibition again either."
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