The pair return to the O2 Arena for the stacked card and will be hoping to replicate their successes inside the Octagon at the same venue back in March, where they both emerged victorious.
And so too will Drake, who has posted his betting slip ahead of the combat sports event.
'Drizzy' has lumped on big for the duo to do the business and will rake in a whopping $3,723,077 (£3,101,401.33) if his bet comes in.
Drake, who is a huge fan of the English culture and brought back the Top Boy series, took to Instagram to share his bet and captioned it, "A scousers parlay.”
Pimblett takes on Jordan Leavitt in the lightweight division, while flyweight McCann is up against Hannah Goldy in the second show at the O2 Arena this year.
They will of course be hoping they don't feel victim to the "Drake curse" - though that was eventually debunked.
The 35-year-old is a massive MMA fan and regularly puts his money where his mouth is when it comes to the biggest fights.
He recently put a massive $1 million on middleweight champion Israel Adesanya beating Jared Cannonier and that came in, though he did lose $275,000 on the UFC 272 main event earlier this year.
Drake tipped Jorge Masvidal to best bitter rival Colby Covington but the former interim UFC welterweight champion dominated the five rounds.
'Champagne Papi' ended up getting rinsed by Covington in the post-fight press conference, before Masvidal offered to make up for his loss by taking Drake out for dinner in Miami.
Drake also put on $1.3 million worth of bitcoin bets on the LA Rams to beat the Cincinnati Bengals in the Super Bowl.
He had $600,000 of bitcoin on the Rams to lift the Vince Lombardi Trophy for the first time in 22 years and also had serious confidence in friend Odell Beckham Jr coming up clutch.
He put on $500,000 on the wide-receiver to amass over 63 yards while on the pitch and a further $500,000 on him registering a touchdown at any point.
Beckham Jr did just that - in the first quarter no less - as the Rams clinched a second Super Bowl title.
Overall he is said to have made more than $1 million from the American Football game.
Featured Image Credit: Image: Alamy & Drake
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